Detail
LncRNA Name | GAS5 |
Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
Region | GRCh38_1:173863900-173868882 Sequence |
Ensembl | ENSG00000234741 |
RefSeq | NR_002578 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | melanoma |
ICD-0-3 | M8720/3 |
Methods | qPCR |
Sample | melanoma tissues, cell lines (A2058, B16, M21, MM200, MEL-RM and A375) |
Expression Pattern | down-regulated |
Function Description | the expression of GAS5 was down-regulated in melanoma tissues compared to adjacent normal tissues. Finally, we suggested that GAS5 inhibited the growth of melanoma through miR-137 in vivo. |
Pubmed ID | 28386376 |
Year | 2017 |
Title | Long non-coding RNA GAS5 inhibits tumorigenesis via miR-137 in melanoma |
External Links |
Links for GAS5 | GenBank HGNC lncrnadb Noncode |
Links for melanoma | Omim Cosmic |
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