Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name GAS5
   Synonyms GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007
   Region GRCh38_1:173863900-173868882    Sequence
   Ensembl ENSG00000234741
   RefSeq NR_002578
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR
   Sample breast cancer tissues
   Expression Pattern differential expression
   Function Description

The expression levels of both genes was lower in the overweight-obese (BMI â?¥ 25) subgroup than that in the normal BMI (BMI < 25) subgroup (GAS5 P = .019, LSINCT5 P = .036). Moreover, the expression level of GAS5 was negatively correlated with BMI (r: _x0001_.170, P: .041). The expression level of GAS5 was higher in women with late menarche (>13 years) than that with early menarche (â?¤13 years; P = .017).

   Pubmed ID 29785740
   Year 2018
   Title Expression levels of breast cancer-related GAS5 and LSINCT5 lncRNAs in cancer-free breast tissue: Molecular associations with age at menarche and obesity
   External Links
   Links for  GAS5 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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