Detail
| LncRNA Name | GAS6-AS2 |
| Synonyms | NA |
| Region | NA Sequence |
| Ensembl | ENSG00000272695 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | M9861/3 |
| Methods | qPCR etc. |
| Sample | cell lines (MOLM14, K562, HEK293, HL60) |
| Expression Pattern | up-regulated |
| Function Description | Transcriptional activation of the GAS6-AS2 lncRNA, identified in our analysis, leads to hyperactivation of the GAS6/TAM pathway, a resistance mechanism in multiple cancers including AML. |
| Pubmed ID | 29677511 |
| Year | 2018 |
| Title | An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance. |
| External Links |
| Links for GAS6-AS2 | GenBank HGNC lncrnadb Noncode |
| Links for acute myeloid leukemia | Omim Cosmic |
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