Detail
| LncRNA Name | AK001796 |
| Synonyms | MIR4435-2HG, AGD2, AK001796, LINC00978, MIR4435-1HG, MIR4435-2HG |
| Region | GRCh38_2:111036776-111523376 Sequence |
| Ensembl | ENSG00000172965 |
| RefSeq | NR_015395 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | esophageal squamous cell cancer |
| ICD-0-3 | |
| Methods | qPCR, Western blot, in vitro knockdown etc |
| Sample | cell lines (Eca-109,TE-1), ESCC tissues |
| Expression Pattern | up-regulated |
| Function Description | lncRNA AK001796 was significantly upregulated in ESCC tumor tissues.lncRNA AK001796 regulates cell proliferation and cell cycle via modulating MDM2/p53 signaling in ESCC, which provides a new insight into the treatment targets for ESCC. |
| Pubmed ID | 29568233 |
| Year | 2018 |
| Title | The long non-coding RNA AK001796 contributes to tumor growth via regulating expression of p53 in esophageal squamous cell carcinoma. |
| External Links |
| Links for AK001796 | GenBank HGNC lncrnadb Noncode |
| Links for esophageal squamous cell cancer | Omim Cosmic |
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