Detail
LncRNA Name | GASL1 |
Synonyms | GASAL1 |
Region | GRCh38_8:102805517-102809971 Sequence |
Ensembl | ENSG00000253669 |
RefSeq | NR_149020 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | osteosarcoma |
ICD-0-3 | M9180/3 |
Methods | qPCR, Western blot etc. |
Sample | cell lines (U2OS and SAOS-2) |
Expression Pattern | up-regulated |
Function Description | The real-time PCR analysis demonstrated that activation of the ectopic E2F1 increased expression of GASL1 in both U2OS and H1299 cell lines. These results demonstrate that GASL1 plays a crucial role in osteosarcoma cell growth in vivo. |
Pubmed ID | 28423601 |
Year | 2017 |
Title | A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity |
External Links |
Links for GASL1 | GenBank HGNC lncrnadb Noncode |
Links for osteosarcoma | Omim Cosmic |
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