Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name GASL1
   Synonyms GASAL1
   Region GRCh38_8:102805517-102809971    Sequence
   Ensembl ENSG00000253669
   RefSeq NR_149020
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name osteosarcoma
   ICD-0-3  M9180/3
   Methods qPCR, Western blot etc.
   Sample cell lines (U2OS and SAOS-2)
   Expression Pattern up-regulated
   Function Description

The real-time PCR analysis demonstrated that activation of the ectopic E2F1 increased expression of GASL1 in both U2OS and H1299 cell lines. These results demonstrate that GASL1 plays a crucial role in osteosarcoma cell growth in vivo.

   Pubmed ID 28423601
   Year 2017
   Title A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity
   External Links
   Links for  GASL1 GenBank       HGNC       lncrnadb       Noncode
   Links for  osteosarcoma Omim       Cosmic

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