Detail
| LncRNA Name | GHET1 |
| Synonyms | GHET1, lncRNA-GHET1 |
| Region | GRCh38_7:148987527-148989432 Sequence |
| Ensembl | ENSG00000281189 |
| RefSeq | NR_130107 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✔ |
| Methylation | ✘ |
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, RNAi, Western blot, in vitro knockdown etc. |
| Sample | bladder cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | In this study, we demonstrated that GHET1 was upregulated in bladder cancer tissues compared to adjacent normal tissues and its over-expression correlates with tumor size, advanced tumor and lymph node status, and poor survival. GHET1 knockdown suppressed the proliferation and invasion of bladder cancer cells in vitro. In the meantime, inhibition of GHET1 reversed the epithelial-mesenchymal-transition in bladder cancer cell line. |
| Pubmed ID | 25400817 |
| Year | 2014 |
| Title | Long noncoding RNA GHET1 promotes the development of bladder cancer. |
| External Links |
| Links for GHET1 | GenBank HGNC lncrnadb Noncode |
| Links for bladder cancer | Omim Cosmic |
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