Detail
| LncRNA Name | GNG12-AS1 |
| Synonyms | GNG12-AS1 |
| Region | GRCh38_1:67832303-68202987 Sequence |
| Ensembl | ENSG00000232284 |
| RefSeq | NR_040077 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, RNAi, ChIP etc. |
| Sample | cell lines (HB2, SUM159, MCF7, K562, Hs27, CAL51, MCF10A etc.) |
| Expression Pattern | down-regulated |
| Function Description | We report that GNG12-AS1 is coexpressed with DIRAS3 in several tissues and coordinately downregulated with DIRAS3 in breast cancers. In breast cancer cell lines with loss of DIRAS3 imprinting, DIRAS3 and GNG12-AS1 are silenced in cis and the remaining GNG12-AS1 transcripts are predominantly monoallelic. |
| Pubmed ID | 23871723 |
| Year | 2013 |
| Title | Imprinted chromatin around DIRAS3 regulates alternative splicing of GNG12-AS1, a long noncoding RNA. |
| External Links |
| Links for GNG12-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.