Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name H19
   Synonyms H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2
   Region GRCh38_11:1995176-2001470    Sequence
   Ensembl ENSG00000130600
   RefSeq NR_002196
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name wilms tumor
   ICD-0-3 C64.9  M8960/3
   Methods qPCR etc.
   Sample Wilms tumor tissues
   Expression Pattern differential expression
   Function Description

Investigating the methylation status of H19DMR revealed a balanced distribution of LOI, ROI and LOH for WT samples. Two-thirds had alterations in H19DMR methylation. Among these samples, 11 had LOI and another 11 LOH. ROI was evident for the remaining 10 tissues. Interestingly, two samples of the nine normal renal tissues had LOI in their H19DMR, while the other ones had ROI.

   Pubmed ID 21174059
   Year 2011
   Title Altered expression of imprinted genes in Wilms tumors.
   External Links
   Links for  H19 GenBank       HGNC       lncrnadb       Noncode
   Links for  wilms tumor Omim       Cosmic

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