Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name H19
   Synonyms H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2
   Region GRCh38_11:1995176-2001470    Sequence
   Ensembl ENSG00000130600
   RefSeq NR_002196
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name acute myeloid leukemia
   ICD-0-3  M9861/3
   Methods Western blot, luciferase reporter assay, etc.
   Sample acute myelocytic leukemia tissues, cell lines (HL-60, HEK-193T)
   Expression Pattern up-regulated
   Function Description

it was demonstrated that the knockdown of lncRNA H19 resulted in increased expression of hsa-microRNA-19a/b and decreased expression of inhibitor of DNA binding 2 (ID2) in AML cells.

   Pubmed ID 28765931
   Year 2017
   Title LncRNA H19 regulates ID2 expression through competitive binding to hsa-miR-19a/b in acute myelocytic leukemia.
   External Links
   Links for  H19 GenBank       HGNC       lncrnadb       Noncode
   Links for  acute myeloid leukemia Omim       Cosmic

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