Detail
LncRNA Name | H19 |
Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
Region | GRCh38_11:1995176-2001470 Sequence |
Ensembl | ENSG00000130600 |
RefSeq | NR_002196 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | acute myeloid leukemia |
ICD-0-3 | M9861/3 |
Methods | Western blot, luciferase reporter assay, etc. |
Sample | acute myelocytic leukemia tissues, cell lines (HL-60, HEK-193T) |
Expression Pattern | up-regulated |
Function Description | it was demonstrated that the knockdown of lncRNA H19 resulted in increased expression of hsa-microRNA-19a/b and decreased expression of inhibitor of DNA binding 2 (ID2) in AML cells. |
Pubmed ID | 28765931 |
Year | 2017 |
Title | LncRNA H19 regulates ID2 expression through competitive binding to hsa-miR-19a/b in acute myelocytic leukemia. |
External Links |
Links for H19 | GenBank HGNC lncrnadb Noncode |
Links for acute myeloid leukemia | Omim Cosmic |
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