Detail
| LncRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 Sequence |
| Ensembl | ENSG00000130600 |
| RefSeq | NR_002196 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR, western blot, luciferase reporter assay |
| Sample | colon cancer tissues, cell lines (SW480, HT-29, colon26, HCT-8, and RKO) |
| Expression Pattern | differential expression |
| Function Description | H19 shRNA strongly reduced the tumor growth and tumor volume. H19 shRNA also inhibited metastasis via suppressing hepatic metastases and the expression of metastasis-related proteins. Taken together, our research indicated an H19-miR138-HMGA1 pathway in regulating the migration and invasion of colon cancer, |
| Pubmed ID | 28358427 |
| Year | 2017 |
| Title | H19 promotes the migration and invasion of colon cancer by sponging miR-138 to upregulate the expression of HMGA1 |
| External Links |
| Links for H19 | GenBank HGNC lncrnadb Noncode |
| Links for colon cancer | Omim Cosmic |
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