Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name H19
   Synonyms H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2
   Region GRCh38_11:1995176-2001470    Sequence
   Ensembl ENSG00000130600
   RefSeq NR_002196
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods qPCR, Northern blot, ISH etc.
   Sample cell lines (HT-1376; UM-UC-3 and T24P)
   Expression Pattern differential expression
   Function Description

It is reexpressed in a number of tumors including bladder carcinoma, demonstrating that H19 RNA is an oncofetal RNA. Tumors induced by injection of bladder carcinoma cell lines express H19 in contrast to the cells before injection. These observations support the notion of a positive correlation between H19 expression and bladder carcinoma. Loss of imprinting of H19 and IGF-2 was observed in samples of human bladder carcinoma.

   Pubmed ID 7589512
   Year 1995
   Title The expression of the imprinted H19 and IGF-2 genes in human bladder carcinoma.
   External Links
   Links for  H19 GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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