Detail
| LncRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 Sequence |
| Ensembl | ENSG00000130600 |
| RefSeq | NR_002196 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, RNAi, Western blot, Luciferase reporter assay etc. |
| Sample | bladder cancer tissues, cell lines (RT4, HT-1376, 5637, 253J, TCCSUP, T24,and J82) |
| Expression Pattern | up-regulated |
| Function Description | We found that miR-675 expression levels were remarkably increased in bladder cancer tissues as compared with adjacent noncancerous tissues or normal bladder tissue from health donors; moreover, enhanced miR-675 expression was also observed in bladder cancer cell lines. Ectopic expression of H19 significantly increased bladder cancer cell proliferation and miR-675 expression in vitro |
| Pubmed ID | 26198047 |
| Year | 2015 |
| Title | H19-derived miR-675 contributes to bladder cancer cell proliferation by regulating p53 activation |
| External Links |
| Links for H19 | GenBank HGNC lncrnadb Noncode |
| Links for bladder cancer | Omim Cosmic |
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