Detail
LncRNA Name | H19 |
Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
Region | GRCh38_11:1995176-2001470 Sequence |
Ensembl | ENSG00000130600 |
RefSeq | NR_002196 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | bladder cancer |
ICD-0-3 | C67 |
Methods | qPCR, RNAi, Western blot etc. |
Sample | cell line (HTB-9, J82), bladder cancer tissues |
Expression Pattern | up-regulated |
Function Description | Up-regulation of H19 in bladder cancer tissues is correlated with clinical stage or metastasis of cancer.By cell transfection to suppress H19 expression in bladder cancer cells,E-cadherin expression is upregulated,thus weakening metastatic potency of cancer cells. |
Pubmed ID | 29614625 |
Year | 2018 |
Title | Inhibition of E-cadherin expression by lnc-RNA H19 to facilitate bladder cancer metastasis. |
External Links |
Links for H19 | GenBank HGNC lncrnadb Noncode |
Links for bladder cancer | Omim Cosmic |
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