Detail
LncRNA Name | H19 |
Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
Region | GRCh38_11:1995176-2001470 Sequence |
Ensembl | ENSG00000130600 |
RefSeq | NR_002196 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR, Western blot |
Sample | GC tissues, GC cell lines (BGC823 and SGC7901) |
Expression Pattern | up-regulated |
Function Description | the expression levels of H19 lncRNA in GC tissue samples were significantly higher when compared with that in matched benign adjacent tissue samples.H19 silenced GC cells exhibited significantly increased let-7c expression and decreased HER2 protein expression levels. |
Pubmed ID | 29207111 |
Year | 2017 |
Title | H19 functions as a competing endogenous RNA to regulate human epidermal growth factor receptor expression by sequestering let-7c in gastric cancer. |
External Links |
Links for H19 | GenBank HGNC lncrnadb Noncode |
Links for gastric cancer | Omim Cosmic |
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