Detail
LncRNA Name | H19 |
Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
Region | GRCh38_11:1995176-2001470 Sequence |
Ensembl | ENSG00000130600 |
RefSeq | NR_002196 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR, Western blot, Luciferase report assay |
Sample | The human breast cancer cell lines (MCF-7 ,MDA-MB-231), human breast tumor tissues |
Expression Pattern | up-regulated |
Function Description | In conclusion, H19 promoted proliferation and invasion of breast cancer through the miR-152/DNMT1 axis, providing a novel mechanism about the occurrence and development of breast cancer. |
Pubmed ID | 28544374 |
Year | 2017 |
Title | Long non-coding RNA H19 promotes the proliferation and invasion of breast cancer through upregulating DNMT1 expression by sponging miR-152. |
External Links |
Links for H19 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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