Detail
LncRNA Name | H19 |
Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
Region | GRCh38_11:1995176-2001470 Sequence |
Ensembl | ENSG00000130600 |
RefSeq | NR_002196 |
Circulating | ✘ |
Drug-resisitant | ✔ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | hepatocellular carcinoma |
ICD-0-3 | C22.0 M8170/3 |
Methods | qPCR, Western blot etc. |
Sample | hepatocellular carcinoma tissues, cell line Huh 7 |
Expression Pattern | down-regulated |
Function Description | The study provides evidence that downregulation of H19 may induce OS and reverse chemotherapy resistance of CD133 cancer stem cells by blocking the MAPK/ERK signaling pathway in HCC. |
Pubmed ID | 29800569 |
Year | 2018 |
Title | Effect of long non-coding RNA H19 on oxidative stress and chemotherapy resistance of CD133+ cancer stem cells via the MAPK/ERK signaling pathway in hepatocellular carcinoma |
External Links |
Links for H19 | GenBank HGNC lncrnadb Noncode |
Links for hepatocellular carcinoma | Omim Cosmic |
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