Detail
LncRNA Name | H19 |
Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
Region | GRCh38_11:1995176-2001470 Sequence |
Ensembl | ENSG00000130600 |
RefSeq | NR_002196 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | glioblastoma |
ICD-0-3 | M9440/3 |
Methods | qPCR, Western blot, etc. |
Sample | GBM cell lines. tissue (PCSCs). |
Expression Pattern | Differential expression |
Function Description | Our results show significant differences between GCSCs and PCSCs in terms of proliferation, ultrastructural peculiarities and, at a lower extent, stemness profile. These differences might be important in view of their potential role as a therapeutic target.Since it has been recently demonstrated the involvement of the long non-coding RNAs (lncRNAs) in the progression of gliomas, the expression of H19 lncRNA, as well as of one of its two mature products miR-675-5p was evaluated in neurospheres. |
Pubmed ID | 29963265 |
Year | 2018 |
Title | Cancer stem cells from peritumoral tissue of glioblastoma multiforme: the possible missing link between tumor development and progression. |
External Links |
Links for H19 | GenBank HGNC lncrnadb Noncode |
Links for glioblastoma | Omim Cosmic |
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