Detail
| LncRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 Sequence |
| Ensembl | ENSG00000130600 |
| RefSeq | NR_002196 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, etc. |
| Sample | lung cancer tissues, cell lines (A549, H1299) |
| Expression Pattern | up-regulated |
| Function Description | we firstly provide new evidence that H19 can induce LIN28B, a conserved RNA binding protein, to accelerate lung cancer growth through sponging miR-196b. Our finding indicates that H19 depresses miR-196b to elevate LIN28B, resulting in accelerating cell proliferation in lung cancer. |
| Pubmed ID | 29950144 |
| Year | 2018 |
| Title | LncRNA H19-elevated LIN28B promotes lung cancer progression through sequestering miR-196b. |
| External Links |
| Links for H19 | GenBank HGNC lncrnadb Noncode |
| Links for lung cancer | Omim Cosmic |
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