Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name H2A/K
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name renal cancer
   ICD-0-3 C64.9  
   Methods qPCR, Cell proliferation assay etc.
   Sample renal cancer tissues, cell line (HEK293T)
   Expression Pattern differential expression
   Function Description

Quantitative proteomic analysis indicated that the expression of mutant H2A/K lncRNAs resulted in the upregulation of many oncogenes, which promoted cell proliferation. Finally, the promotion of cell proliferation by mutant H2A/K lncRNAs (C290T, C228A and A45G) was confirmed using cell proliferation assays.

   Pubmed ID 26953487
   Year 2016
   Title H2A/K pseudogene mutation may promote cell proliferation.
   External Links
   Links for  H2A/K GenBank       HGNC       lncrnadb       Noncode
   Links for  renal cancer Omim       Cosmic

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