Detail
LncRNA Name | H2A/K |
Synonyms | NA |
Region | NA Sequence |
Ensembl | NA |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✔ |
Methylation | ✘ |
Cancer Name | renal cancer |
ICD-0-3 | C64.9 |
Methods | qPCR, Cell proliferation assay etc. |
Sample | renal cancer tissues, cell line (HEK293T) |
Expression Pattern | differential expression |
Function Description | Quantitative proteomic analysis indicated that the expression of mutant H2A/K lncRNAs resulted in the upregulation of many oncogenes, which promoted cell proliferation. Finally, the promotion of cell proliferation by mutant H2A/K lncRNAs (C290T, C228A and A45G) was confirmed using cell proliferation assays. |
Pubmed ID | 26953487 |
Year | 2016 |
Title | H2A/K pseudogene mutation may promote cell proliferation. |
External Links |
Links for H2A/K | GenBank HGNC lncrnadb Noncode |
Links for renal cancer | Omim Cosmic |
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