Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HCP5
   Synonyms D6S2650E, P5-1
   Region GRCh38_6:31400702-31477506    Sequence
   Ensembl ENSG00000206337
   RefSeq NR_040662
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung adenocarcinoma
   ICD-0-3 C34  M8140/3
   Methods qPCR
   Sample lung adenocarcinoma tissues
   Expression Pattern down-regulated
   Function Description

Our study sheds novel light on the roles of lncRNA-related ceRNA network in LAD and facilitates the detection of potential lncRNA biomarkers for LAD diagnosis and treatment. Remarkably, in our study, LINC00472, HCP5, and SNHG12 might be potential biomarkers for LAD management.As we all know, histones constantly undergo post-translational modifications, for instance, methylation, acetylation.Typically, lncRNA functions are characterized using a â??guilt by associationâ??strategy. It has been reported that lncRNAs harboring miRNA response elements (MREs) serve as competing endogenous RNAs (ceRNAs) to exchange with mRNAs via competing for common miRNAs.

   Pubmed ID 28793054
   Year 2017
   Title Revealing potential long non-coding RNA biomarkers in lung adenocarcinoma using long non-coding RNA-mediated competitive endogenous RNA network.
   External Links
   Links for  HCP5 GenBank       HGNC       lncrnadb       Noncode
   Links for  lung adenocarcinoma Omim       Cosmic

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