Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HIF1A-AS1
   Synonyms HIF1A-AS1, 5'aHIF-1A, 5'aHIF1alpha
   Region GRCh38_14:61681041-61695823    Sequence
   Ensembl ENSG00000258777
   RefSeq NR_047116
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR
   Sample colon cancer tissues
   Expression Pattern up-regulated
   Function Description

differentiation degree, tumor size, TNM stage, T stage, N stage, M stage and serum level of HIF1A-AS1 were all linked to CRC prognosis.Compared to CRC patients with low HIF1A-AS1 expression, high expression of patients were associated with a shorter 5-year-survival rate. lower differentiation degree, tumor > 5cm and higher expression of HIF1A-AS1 were independent risk factors affecting the survival rate of patients with CRC.

   Pubmed ID 28946548
   Year 2017
   Title Elevated serum level of lncRNA-HIF1A-AS1 as a novel diagnostic predictor for worse prognosis in colorectal carcinoma.
   External Links
   Links for  HIF1A-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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