Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HIF1A-AS1
   Synonyms HIF1A-AS1, 5'aHIF-1A, 5'aHIF1alpha
   Region GRCh38_14:61681041-61695823    Sequence
   Ensembl ENSG00000258777
   RefSeq NR_047116
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR etc.
   Sample plasma, gastric cancer tissues
   Expression Pattern down-regulated
   Function Description

We further analyzed the expression of the top 2 downregulated and up-regulated lncRNAs in 20 GC tissues and corresponding nontumourous tissues by qRT-PCR. The expression of HIF1A-AS1 and PVT1 drastically decreased in GC tumor tissues. Conversely, the expression of CBR3-AS1 and UCA1 increased.

   Pubmed ID 26722487
   Year 2015
   Title Long non-coding RNA UCA1 may be a novel diagnostic and predictive biomarker in plasma for early gastric cancer.
   External Links
   Links for  HIF1A-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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