Detail
| LncRNA Name | HIF1A-AS2 |
| Synonyms | HIF1A-AS2, 3'aHIF-1A, aHIF |
| Region | GRCh38_14:61715558-61751097 Sequence |
| Ensembl | ENSG00000258667 |
| RefSeq | NR_045406 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qRT-PCR, Western blot, Luciferase reporter assay, RIP |
| Sample | human CRC tissues, Human CRC cell lines (SW620, DLD-1, HT-29, HCT116) |
| Expression Pattern | up-regulated |
| Function Description | immunofluorescence, all those assays reflected a fact that as a ceRNA, HIF1A-AS2 could directly bind with miR-129-5p, and could positively affect cell proliferation, invasion and EMT formation by regulation of the expression of miR-129-5p and DNMT3A. |
| Pubmed ID | 29278853 |
| Year | 2017 |
| Title | LncRNA HIF1A-AS2 positively affects the progression and EMT formation of colorectal cancer through regulating miR-129-5p and DNMT3A. |
| External Links |
| Links for HIF1A-AS2 | GenBank HGNC lncrnadb Noncode |
| Links for colorectal cancer | Omim Cosmic |
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