Detail
LncRNA Name | HIF1A-AS2 |
Synonyms | HIF1A-AS2, 3'aHIF-1A, aHIF |
Region | GRCh38_14:61715558-61751097 Sequence |
Ensembl | ENSG00000258667 |
RefSeq | NR_045406 |
Circulating | ✔ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | microarray, qPCR, RNAi, Cell proliferation assay, Cell invasion assay etc. |
Sample | breast cancer tissues, cell lines (MDA-MB-231, BT549, Hs578T and 293T) |
Expression Pattern | up-regulated |
Function Description | lncRNAs HIF1A-AS2 and AK124454 could promote cell proliferation and invasion, and attenuate G2-M arrest, which might contribute to paclitaxel resistance in TNBC cells. |
Pubmed ID | 26921339 |
Year | 2016 |
Title | Transcriptome Analysis of Triple-Negative Breast Cancer Reveals an Integrated mRNA-lncRNA Signature with Predictive and Prognostic Value. |
External Links |
Links for HIF1A-AS2 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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