Detail
| LncRNA Name | HMMR-AS1 |
| Synonyms | NA |
| Region | GRCh38_5:163483065-163494058 Sequence |
| Ensembl | ENSG00000251018 |
| RefSeq | NR_109892 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, RNAi, Luciferase reporter assay etc. |
| Sample | breast cancer tissues, cell lines (MDA-MB-231 and MDA-MB-468) |
| Expression Pattern | up-regulated |
| Function Description | We found that the expression of HMMR was positively correlated with HMMR-AS1 (RP11-80G.1). When HMMR-AS1 (RP11-80G.1) was knocked down, the expression of HMMR markedly reduced. Furthermore, in MDA-MB-231 and MDA-MB-468 breast cancer cells, the proliferation and migration abilities were remarkably suppressed via knocking down HMMR-AS1 (RP11-80G.1) in vitro. |
| Pubmed ID | 27920576 |
| Year | 2016 |
| Title | The HMMR-AS1 expression was markedly higher in BLBCs in contrast to those in non-BLBC subtypes. HMMR antisense RNA 1, a novel long noncoding RNA, regulates the progression of basal-like breast cancer cells. |
| External Links |
| Links for HMMR-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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