Detail
| LncRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 Sequence |
| Ensembl | ENSG00000228630 |
| RefSeq | NR_003716 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | blood |
| Expression Pattern | up-regulated |
| Function Description | Plasma long non-coding HOTAIR as anon-invasive biomarker in GC.Plasma HOTAIR was significantly up-regulated in GC patients compared with controls.HOTAIR may also serve as a competitive endogenous RNA (ceRNA). In GC, it prevents transcriptional suppression of HER2 mRNA through competition for miR-331-3p. |
| Pubmed ID | 29683069 |
| Year | 2018 |
| Title | Plasma long non-coding RNA HOTAIR as a potential biomarker for gastric cancer. |
| External Links |
| Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
| Links for gastric cancer | Omim Cosmic |
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