Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOTAIR
   Synonyms HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072
   Region GRCh38_12:53962308-53974956    Sequence
   Ensembl ENSG00000228630
   RefSeq NR_003716
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name osteosarcoma
   ICD-0-3  M9180/3
   Methods qPCR etc.
   Sample blood
   Expression Pattern up-regulated
   Function Description

The expression level of HOTAIR in OS tissues was significantly higher than that in corresponding normal tissues. Subjects with the rs7958904 CC genotype had significantly lower HOTAIR RNA levels than those with the GG genotypes in normal and OS tissues.

   Pubmed ID 26967389
   Year 2016
   Title Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma.
   External Links
   Links for  HOTAIR GenBank       HGNC       lncrnadb       Noncode
   Links for  osteosarcoma Omim       Cosmic

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