Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOTAIR
   Synonyms HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072
   Region GRCh38_12:53962308-53974956    Sequence
   Ensembl ENSG00000228630
   RefSeq NR_003716
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample serum
   Expression Pattern up-regulated
   Function Description

We found that total HOTAIR was effectively amplified by most of the primers, suggesting the presence of HOTAIR in serum. The primer pair for 2-1 showed the highest amplification efficiency, and the PCR product was confirmed by gel detection and sequencing

   Pubmed ID 26033707
   Year 2015
   Title Circulating DNA of HOTAIR in serum is a novel biomarker for breast cancer.
   External Links
   Links for  HOTAIR GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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