Detail
| LncRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 Sequence |
| Ensembl | ENSG00000228630 |
| RefSeq | NR_003716 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | diffuse Large B-Cell Lymphoma |
| ICD-0-3 | M9680/3 |
| Methods | qPCR |
| Sample | Lymphoma tissues |
| Expression Pattern | differential expression |
| Function Description | HOTAIR expression could be one of possible mechanisms for inducing H3K27me3 via EZH2-related PRC2 activation, and induced H3K27me3 may be strongly related to aggressive DLBCLs which show poor patient outcome. In Relation to Polycomb Repressive Complex Pathway Proteins and H3K27 Trimethylation |
| Pubmed ID | 27550047 |
| Year | 2016 |
| Title | Long Non-coding RNA HOTAIR Expression in Diffuse Large B-Cell Lymphoma: In Relation to Polycomb Repressive Complex Pathway Proteins and H3K27 Trimethylation |
| External Links |
| Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
| Links for diffuse Large B-Cell Lymphoma | Omim Cosmic |
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