Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOTAIR
   Synonyms HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072
   Region GRCh38_12:53962308-53974956    Sequence
   Ensembl ENSG00000228630
   RefSeq NR_003716
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colon cancer
   ICD-0-3 C18  
   Methods qPCR etc.
   Sample colon cancer tissues
   Expression Pattern up-regulated
   Function Description

The expression of HOTAIR was significantly higher in colon cancer tissues than in matched tumor-adjacent normal colon tissues. HOTAIR expression was significantly higher in cases with lymph node metastasis than in those without metastasis; in lowly differentiated and undifferentiated cases than in highly and moderately differentiated cases; and in stages III + IV cases than in stagesI+ II cases.

   Pubmed ID 27298568
   Year 2016
   Title Clinical significance of HOTAIR expression in colon cancer.
   External Links
   Links for  HOTAIR GenBank       HGNC       lncrnadb       Noncode
   Links for  colon cancer Omim       Cosmic

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