Detail
LncRNA Name | HOTAIR |
Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
Region | GRCh38_12:53962308-53974956 Sequence |
Ensembl | ENSG00000228630 |
RefSeq | NR_003716 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colon cancer |
ICD-0-3 | C18 |
Methods | qPCR etc. |
Sample | colon cancer tissues |
Expression Pattern | up-regulated |
Function Description | The expression of HOTAIR was significantly higher in colon cancer tissues than in matched tumor-adjacent normal colon tissues. HOTAIR expression was significantly higher in cases with lymph node metastasis than in those without metastasis; in lowly differentiated and undifferentiated cases than in highly and moderately differentiated cases; and in stages III + IV cases than in stagesI+ II cases. |
Pubmed ID | 27298568 |
Year | 2016 |
Title | Clinical significance of HOTAIR expression in colon cancer. |
External Links |
Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
Links for colon cancer | Omim Cosmic |
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