Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name AB073614
   Synonyms NA
   Region GRCh38_3:149173591-149175492    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name glioma
   ICD-0-3  M9380/3
   Methods qPCR, RNAi, Western blot, Cell proliferation assay etc.
   Sample glioma tissues, cell line (U251)
   Expression Pattern up-regulated
   Function Description

We confirmed that AB073614 was significantly upregulated in glioma tissues and cell lines. In vitro studies demonstrated that knockdown of AB073614 inhibits U251 cell proliferation and migration. Moreover, knockdown of AB073614 could inhibit epithelial-mesenchymal transition (EMT) phenotype in glioma cells.

   Pubmed ID 27775800
   Year 2016
   Title Knockdown of long noncoding RNA AB073614 inhibits glioma cell proliferation and migration via affecting epithelial-mesenchymal transition.
   External Links
   Links for  AB073614 GenBank       HGNC       lncrnadb       Noncode
   Links for  glioma Omim       Cosmic

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