Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOTAIR
   Synonyms HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072
   Region GRCh38_12:53962308-53974956    Sequence
   Ensembl ENSG00000228630
   RefSeq NR_003716
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods Western blot, qPCR, ChIP
   Sample cell lines (T24, UM-UC-3)
   Expression Pattern up-regulated
   Function Description

Silibinin was found to significantly decrease the expression levels of oncogenic HOTAIR and ZFAS

   Pubmed ID 29190895
   Year 2017
   Title Silibinin suppresses bladder cancer through down-regulation of actin cytoskeleton and PI3K/Akt signaling pathways
   External Links
   Links for  HOTAIR GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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