Detail
LncRNA Name | HOTAIR |
Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
Region | GRCh38_12:53962308-53974956 Sequence |
Ensembl | ENSG00000228630 |
RefSeq | NR_003716 |
Circulating | ✘ |
Drug-resisitant | ✔ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | bladder cancer |
ICD-0-3 | C67 |
Methods | Western blot, qPCR, ChIP |
Sample | cell lines (T24, UM-UC-3) |
Expression Pattern | up-regulated |
Function Description | Silibinin was found to significantly decrease the expression levels of oncogenic HOTAIR and ZFAS |
Pubmed ID | 29190895 |
Year | 2017 |
Title | Silibinin suppresses bladder cancer through down-regulation of actin cytoskeleton and PI3K/Akt signaling pathways |
External Links |
Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
Links for bladder cancer | Omim Cosmic |
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