Detail
| LncRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 Sequence |
| Ensembl | ENSG00000228630 |
| RefSeq | NR_003716 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, RNAi, Western blot etc. |
| Sample | urine, cell lines (SV-HUC, 5637, TCC-SUP, T24, UMUC3, HT1376, J82, and RT4) |
| Expression Pattern | up-regulated |
| Function Description | Here we show HOTAIR and several tumor-associated lncRNAs are enriched in UEs from UBC patients with high-grade muscle-invasive disease (HGMI pT2-pT4). Knockdown of HOTAIR in UBC cell lines reduces in vitro migration and invasion. |
| Pubmed ID | 26800519 |
| Year | 2016 |
| Title | Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes. |
| External Links |
| Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
| Links for bladder cancer | Omim Cosmic |
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