Detail
| LncRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 Sequence |
| Ensembl | ENSG00000228630 |
| RefSeq | NR_003716 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qPCR, Western blot, RIP |
| Sample | renal cell carcinoma tissues, cell lines (769-P and ACHN) |
| Expression Pattern | up-regulated |
| Function Description | HOTAIR expression was upregulated, which was correlated with tumor progression, and miR-217 downregulated in Rcc tissues and cells.Importantly,HOTAIR expression was negatively correlated with miR-217 expression in Rcc tissues. |
| Pubmed ID | 28492542 |
| Year | 2017 |
| Title | LncRNA HOTAIR regulates HIF-1a/AXL signaling through inhibition of miR-217 in renal cell carcinoma |
| External Links |
| Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
| Links for renal cell carcinoma | Omim Cosmic |
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