Detail
LncRNA Name | HOTAIR |
Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
Region | GRCh38_12:53962308-53974956 Sequence |
Ensembl | ENSG00000228630 |
RefSeq | NR_003716 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 M8046/3 |
Methods | qPCR, Western blot, Luciferase reporter assay etc. |
Sample | cell lines (H1299, H23, H292, A549) |
Expression Pattern | up-regulated |
Function Description | Down-regulation of HOTAIR suppressed tumorigenesis and metastasis of NSCLC via up-regulating the expression of miR-613. |
Pubmed ID | 29187267 |
Year | 2017 |
Title | LncRNA-HOTAIR affects tumorigenesis and metastasis of non-small cell lung cancer by up-regulating miR-613 |
External Links |
Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
Links for non small cell lung cancer | Omim Cosmic |
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