Detail
| LncRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 Sequence |
| Ensembl | ENSG00000228630 |
| RefSeq | NR_003716 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot etc. |
| Sample | cell lines (SKOV3, ES-2, OVCAR3, A2780, and COC1) |
| Expression Pattern | down-regulated |
| Function Description | In this study, we report that HOTAIR may function as a ceRNA to regulate the expression of MAPK1 through competition for miR-1, miR-214-3p, or miR-330-5p in ovarian SKOV3 cells, providing a new insight in the treatment of ovarian cancer. |
| Pubmed ID | 26117268 |
| Year | 2015 |
| Title | HOTAIR Interacting with MAPK1 Regulates Ovarian Cancer skov3 Cell Proliferation, Migration, and Invasion |
| External Links |
| Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
| Links for ovarian cancer | Omim Cosmic |
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