Detail
| LncRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 Sequence |
| Ensembl | ENSG00000228630 |
| RefSeq | NR_003716 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, RNAi, Luciferase reporter assay |
| Sample | cell lines (KURAMOCHI, A2780p, A2780_CR5) |
| Expression Pattern | differential expression |
| Function Description | Treatment of HOTAIR-overexpressing ovarian and breast cancer cell lines with PNAs decreased invasion and increased chemotherapy sensitivity. |
| Pubmed ID | 28420874 |
| Year | 2017 |
| Title | Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancer |
| External Links |
| Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
| Links for ovarian cancer | Omim Cosmic |
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