Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOTAIR
   Synonyms HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072
   Region GRCh38_12:53962308-53974956    Sequence
   Ensembl ENSG00000228630
   RefSeq NR_003716
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR
   Sample hepatocellular carcinoma tissues
   Expression Pattern differential expression
   Function Description

Significant associations were observed between the HOTAIR rs920778 C>T polymorphism and HCC risk (TT versus CC: OR = 1.634, 95% CI =1.028-2.598, P = 0.046) and the allelic model (allele T versus allele C: OR =1.293, 95% CI = 1.060-1.577, P = 0.011).

   Pubmed ID 29141248
   Year 2017
   Title Association of Functional Genetic Variants of HOTAIR with Hepatocellular Carcinoma (HCC) Susceptibility in a Chinese Population
   External Links
   Links for  HOTAIR GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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