Detail
| LncRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 Sequence |
| Ensembl | ENSG00000228630 |
| RefSeq | NR_003716 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | glioma |
| ICD-0-3 | M9380/3 |
| Methods | qPCR, RNAi, Western blot, ChIP, Cell proliferation assay etc. |
| Sample | glioma tissues, cell lines (U251, U87, LN-18 and H4) |
| Expression Pattern | up-regulated |
| Function Description | The expression of HOTAIR was significantly increased in glioma cells compared with normal cells, and it exerted its function in a polycomb repressive complex 2-dependent manner. |
| Pubmed ID | 28105224 |
| Year | 2016 |
| Title | Suppression of PDCD4 mediated by the long non-coding RNA HOTAIR inhibits the proliferation and invasion of glioma cells. |
| External Links |
| Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
| Links for glioma | Omim Cosmic |
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