Detail
| LncRNA Name | AK123263 |
| Synonyms | LOC100506974 |
| Region | GRCh38_17:13776832-13777349 Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 M8046/3 |
| Methods | microarray, qPCR, RNAi, Western blot etc. |
| Sample | cell lines (A549, CDDP etc.) |
| Expression Pattern | down-regulated |
| Function Description | For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP. Cisplatin resistance in non-small-cell lung cancer cells may relate to the changes in noncoding RNAs. Among these, AK126698 appears to confer cisplatin resistance by targeting the Wnt pathway. |
| Pubmed ID | 23741487 |
| Year | 2013 |
| Title | The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell. |
| External Links |
| Links for AK123263 | GenBank HGNC lncrnadb Noncode |
| Links for non small cell lung cancer | Omim Cosmic |
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