Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOTAIR
   Synonyms HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072
   Region GRCh38_12:53962308-53974956    Sequence
   Ensembl ENSG00000228630
   RefSeq NR_003716
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample blood, breast cancer tissues
   Expression Pattern up-regulated
   Function Description

The expression levels of HOTAIR were significantly higher in BC tissues and plasma than in the control. The expression levels of plasma HOTAIR were correlated with lymph node metastasis, estrogen receptor, c-erbB-2 and triple positive.

   Pubmed ID 27755794
   Year 2016
   Title Circulating long non-coding HOX transcript antisense intergenic ribonucleic acid in plasma as a potential biomarker for diagnosis of breast cancer.
   External Links
   Links for  HOTAIR GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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