Detail
LncRNA Name | HOTAIR |
Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
Region | GRCh38_12:53962308-53974956 Sequence |
Ensembl | ENSG00000228630 |
RefSeq | NR_003716 |
Circulating | ✔ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR etc. |
Sample | gastric cancer tissues, cell lines (AGS, MKN45, 7901 etc.) |
Expression Pattern | up-regulated |
Function Description | All the 8 lncRNAs were then subjected to qPCR validation using 20 pairs of GC and control tissues. Among them, HOTAIR, PVT1, H19, MALAT1, GHET1 and HULC were significantly higher in tumor tissues compared with control tissues. |
Pubmed ID | 26096073 |
Year | 2015 |
Title | Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer. |
External Links |
Links for HOTAIR | GenBank HGNC lncrnadb Noncode |
Links for gastric cancer | Omim Cosmic |
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