Detail
| LncRNA Name | AK124454 |
| Synonyms | LOC105372310 |
| Region | GRCh38_19:20220597-20222169 Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | microarray, qPCR, RNAi, Cell proliferation assay, Cell invasion assay etc. |
| Sample | breast cancer tissues, cell lines (MDA-MB-231, BT549, Hs578T and 293T) |
| Expression Pattern | up-regulated |
| Function Description | lncRNAs HIF1A-AS2 and AK124454 could promote cell proliferation and invasion, and attenuate G2-M arrest, which might contribute to paclitaxel resistance in TNBC cells. |
| Pubmed ID | 26921339 |
| Year | 2016 |
| Title | Transcriptome Analysis of Triple-Negative Breast Cancer Reveals an Integrated mRNA-lncRNA Signature with Predictive and Prognostic Value. |
| External Links |
| Links for AK124454 | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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