Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name AB074278
   Synonyms NA
   Region GRCh38_17:63039470-63041178    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name urothelial cancer
   ICD-0-3  M8120/3
   Methods microarray, qPCR, RNAi, in vitro knockdown etc.
   Sample urothelial carcinoma of the bladder tissues
   Expression Pattern up-regulated
   Function Description

AB074278 was chosen because it was significantly upregulated in all tumour phenotypes, strongly associated with tumour progression, and has a low protein coding potential score.AB074278 in apoptosis avoidance and the maintenance of a pro-proliferative state in cancer through a potential interaction with EMP1, a tumour suppressor and a negative regulator of cell proliferation.

   Pubmed ID 25165097
   Year 2014
   Title Identification of differentially expressed long noncoding RNAs in bladder cancer.
   External Links
   Links for  AB074278 GenBank       HGNC       lncrnadb       Noncode
   Links for  urothelial cancer Omim       Cosmic

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