Detail
| LncRNA Name | HOTTIP |
| Synonyms | HOTTIP, HOXA-AS6, HOXA13-AS1, NCRNA00213 |
| Region | GRCh38_7:27198575-27207259 Sequence |
| Ensembl | ENSG00000243766 |
| RefSeq | NR_037843 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | microarray, qPCR etc. |
| Sample | pancreatic cancer tissues, cell lines (PANC-1, BxPC-3, Capan2, MIAPaCa-2, SW1990, and AsPC-1) |
| Expression Pattern | up-regulated |
| Function Description | Compared with the HPDE6 cells, all PC cell lines had higher HOTTIP-005, XLOC_006390, and RP11-567G11.1 expression. The most increased lncRNAs in PC tissues were HOTTIP-005, XLOC_006390, and RP11-567G11.1. Increased HOTTIP-005 and RP11-567G11.1 expression were poor prognostic factors for patients with PC. |
| Pubmed ID | 26447755 |
| Year | 2015 |
| Title | Expression profile of long non-coding RNAs in pancreatic cancer and their clinical significance as biomarkers. |
| External Links |
| Links for HOTTIP | GenBank HGNC lncrnadb Noncode |
| Links for pancreatic cancer | Omim Cosmic |
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