Detail
LncRNA Name | HOTTIP |
Synonyms | HOTTIP, HOXA-AS6, RP1-170O19.3, HOXA13-AS1 |
Region | GRCh38_7:27198575-27207259 Sequence |
Ensembl | ENSG00000243766 |
RefSeq | NR_037843 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR etc. |
Sample | GC tissues, cell lines (MGC-803, BGC-823, SGC-7901 and HGC-27) |
Expression Pattern | down-regulated |
Function Description | Li et al reported that HOTTIP was upregulated in pancreatic cancer and may promote cancer cell proliferation, invasion and chemoresistance by regulating HOXA13.Survival rates, including overall survival and disease-free survival were calculated using the Kaplan-Meier method with the log-rank test applied for comparison. A receiver operating characteristic (ROC) curve was used to evaluate the diagnostic value of HOTTIP expression levels. |
Pubmed ID | 28693275 |
Year | 2017 |
Title | Long non-coding RNA HOXA transcript at the distal tip as a biomarker for gastric cancer. |
External Links |
Links for HOTTIP | GenBank HGNC lncrnadb Noncode |
Links for gastric cancer | Omim Cosmic |
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