Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOXA11-AS
   Synonyms HOXA11-AS, HOXA-AS5, HOXA11-AS1, HOXA11AS, HOXA11S, NCRNA00076
   Region GRCh38_7:27184518-27189293    Sequence
   Ensembl ENSG00000240990
   RefSeq NR_002795
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR etc.
   Sample CRC tissues, cell lines (HCT8, HCT116 and RKO)
   Expression Pattern down-regulated
   Function Description

The results demonstrated that HOXA11-AS expression was decreased in the CRC tissues and cell lines compared with that of the controls. Clinicopathological analysis indicated that low HOXA11-AS expression was significantly correlated with tumor size, advanced tumor-node-metastasis stage, lymph node metastasis and carcinoembryonic antigen level of patients with CRC.

   Pubmed ID 27895785
   Year 2016
   Title Expression and clinicopathological significance of the lncRNA HOXA11-AS in colorectal cancer.
   External Links
   Links for  HOXA11-AS GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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