Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOXA11-AS
   Synonyms HOXA11-AS, HOXA-AS5, HOXA11-AS1, HOXA11AS, HOXA11S, NCRNA00076
   Region GRCh38_7:27184518-27189293    Sequence
   Ensembl ENSG00000240990
   RefSeq NR_002795
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods qPCR, RIP, Western blotting etc.
   Sample NSCLC tissues, cell lines (A549, H1299, 95D)
   Expression Pattern up-regulated
   Function Description

upregulation of lncRNA HOXA11-AS predicted a poor prognosis and lncRNA HOXA11-AS promoted cell epithelial-mesenchymal transition (EMT) by inhibiting miR-200b expression in NSCLC.

   Pubmed ID 28615992
   Year 2017
   Title Overexpression of lncRNA HOXA11-AS promotes cell epithelialâ??mesenchymal transition by repressing miR-200b in non-small cell lung cancer
   External Links
   Links for  HOXA11-AS GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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