Detail
| LncRNA Name | AK130275 |
| Synonyms | PAX8-AS1 |
| Region | GRCh38_2:113211522-113276581 Sequence |
| Ensembl | ENSG00000189223 |
| RefSeq | NR_015377 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | malignant pleural mesothelioma |
| ICD-0-3 | M9050/3 |
| Methods | microarray, qPCR etc. |
| Sample | MPM tissues, cell lines (H28, H226, H2052, H2452, MSTO etc.) |
| Expression Pattern | up-regulated |
| Function Description | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. |
| Pubmed ID | 23976967 |
| Year | 2013 |
| Title | Long non coding RNAs (lncRNAs) are dysregulated in Malignant Pleural Mesothelioma (MPM). |
| External Links |
| Links for AK130275 | GenBank HGNC lncrnadb Noncode |
| Links for malignant pleural mesothelioma | Omim Cosmic |
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