Detail
| LncRNA Name | HOXA-AS2 |
| Synonyms | HOXA-AS2, HOXA3as |
| Region | GRCh38_7:27107777-27134302 Sequence |
| Ensembl | ENSG00000253552 |
| RefSeq | NR_122069 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Luciferase report assay etc. |
| Sample | breast cancer tissues, cell lines (MCF-10A, MDA-MB-231, MDA-MB-453, and MCF-7) |
| Expression Pattern | up-regulated |
| Function Description | HOXA-AS2 was up-regulated in human breast cancer tissues and cell lines and associated with clinicopathological characteristics. HOXA-AS2 may be a potential prognostic and therapeutic target in breast cancer. HOXA-AS2 controls the expression of miR-520c-3p target genes, TGFBR2 and RELA, in breast cancer cells. |
| Pubmed ID | 28545023 |
| Year | 2017 |
| Title | Long non-coding RNA HOXA-AS2 promotes proliferation and invasion of breast cancer by acting as a miR-520c-3p sponge. |
| External Links |
| Links for HOXA-AS2 | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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